Questions for EXAM and example of TICKET on exam
QUESTIONS FOR EXAM 5 COURSE SPECIAL PHARMACEUTICAL TECHNOLOGY
Level 1 - knowledge assessment
1. Give an answer to the theoretical question:
1. Material balance. Material balance equation. Technological output, technological waste, consumption coefficient: how to calculate them. Present material balance in the form of a table for this case: When grinding 50 kg of streptocidum in a ball mill, 49 kg of crushed product was obtained. Find the exit, waste and consumption coefficient.
2. Theoretical foundations of pressing. The device and principle of operation of tablet machines (Rotary Tablet Machine). Basic theories about the nature of bond in tablets. The nature of the compaction of materials. Technological properties of bulk materials (fractional composition, porosity, bulk density, relative density, compaction coefficient, fluidity, compressibility, force of expulsion of tablets from the matrix).
3. Physical and chemical properties of bulk materials (shape and size of particles, density, specific surface area, true density, contact friction, wettability, hygroscopicity, electrical properties, crystallization water).
4. The main criteria for the standardization of tablets. Apparatus used (devices for determining the rate of dissolution, disintegration of tablets, compressive strength and abrasion).
5. Wet and dry granulation in tablet production. Equipment (granulators, mixer-granulators).
6. Sterilisation, classification of sterilization methods. Heat sterilization (with flowing steam, hot air sterilization, high frequency currents).
7. Manufacture of Liniments in pharmaceutical factory. Classification of liniments. Features of liniment technology: Liniments-solutions, Liniment-emulsions, liniments-suspensions. Methods for preparing liniment (mixing and grinding in a liquid medium). Equipment (turbine atomizer, RPA, rotary hammer mill, vibro-cavitation mill). Features of the technology of aloe liniment, balsamic liniment Wishnevsky, syntomycin liniment. Assessment of the quality of liniments.
8. Water treatment. Water for injection. Requirements for it. Obtaining demineralized water, purified water and water for injection. The equipment used to obtain water at the factory.
9. Grinding. Features of grinding solids. The main methods of grinding. Energy of consumption. Machines used for medium and fine grinding (grass and root cutters, roller crushers, dismembrator and disintegrator), fine grinding (drum, ball and rod mills) and ultrafine grinding (vibratory and jet mills).
10. Coating of tablets. Classification and characteristic of coatings. Auxiliary substances for coatings. Film coating of tablets. Classification of film formers and list of them.
11. Equipment for the production of ointments in the factory. Standardization and quality control of ointments. Methods "in vivo", "in vitro" as the main criteria for assessing the quality of ointments. Packing and packaging of ointments. Equipment for this process.
12. Plasters as a dosage form. Classification. A simple lead plaster. An assortment of plasters prepared on the basis of a simple lead plaster. Rubber plasters. Classification. Nomenclature. Production of bactericidal, corn and pepper adhesive plaster.
13. Separation of crushed materials (mechanical and hydraulic). Apparatus used (wicker sieves, stamped sieves, grate sieves, swing sieves, vibrating sieves).
14. Dosage forms for the eyes. Characteristic. Classification. Requirements for them. Technological scheme for obtaining eye drops. Features of the technology of sodium sulfacyl solution, pilocarpine hydrochloride solution for eye drops. Ophthalmic medicinal films as a dosage form. Technological scheme of production. Nomenclature.
15. Types of packaging of tablets. Automatic and semi-automatic machines for packing and packaging tablets.
16. Gelatin capsules.General characteristic of dosage form. Classification of capsules. Drip production of gelatin capsules. Equipment for this process.
17. Preparation of solutions for ampulation (dissolution, filtration). Filters. Filtering materials. Equipment filtering.
18. Methods for prolonging the action of medicinal substances. Prolonged dosage forms. Characteristic. Requirements for prolonged dosage forms.
19. Medical aerosols. Classification of medical aerosols. Characteristics, classification and nomenclature of propellants. Design and principle of operation of an aerosol can. Aerosols for external use (hyposol, olazol). Medical aerosols for inhalation use (inhalipt, cameton).
20. Suppositories as a dosage form. Classification by method of application. Suppository bases, it’s classification and requirements for them. Characteristic of suppository bases. The equipment used in the production of suppositories in the factory (Franco-Crespi machine, Servac-200S). Evaluation of the quality of suppositories.
21. Ampoules as containers and their characteristics. Chemical properties of glass. Determination of chemical and thermal resistance of glass. Manufacturing of ampoules (molding, opening, annealing). Equipment for this process. Methods for washing ampoules (syringe, vacuum, steam condensation, thermal, vibration). Methods of filling ampoules (syringe, vacuum, steam condensation) with injectable solutions.
22. Infusion solutions. Physiological and blood replacement solutions, requirements for them, their classification. Anti-shock solutions. Solutions for special purposes (Hemodez, Disol, Trisol, Acesol, etc.). Features of the technology of Ringer-Locke solutions, Polyglucin, Reopolyglucin.
23. The nature of pyrogenic substances. Ways of contamination of injection solutions with pyrogenic substances. Methods for the detection of pyrogenic substances.
24. Ointments in factory production. Classification of ointments. Ointment bases Ointment alloys, ointment solutions. Equipment to obtain ointments in the industrial conditions.
25. Microcapsules. Physical methods for obtaining microcapsules. Methods for pelleting, spraying, dispersing in immiscible liquids. Chemical methods of obtaining microcapsules. Physicochemical methods of microencapsulation (simple and complex coacervation). Examples of the use of microencapsulated dosage forms.
26. Ointments in factory production. Ointments bases. Requirements for them. Classification of ointment bases. Technological process of obtaining ointments. Ointments - suspensions. Combined ointments. Features of their technology. Equipment used in the production of ointments.
27. Transdermal therapeutic systems. Characteristic. Structure of them. Application. Nomenclature.
28. Hard and soft gelatin capsules. Obtaining soft gelatin capsules by immersion and pressing.
29. Powders and Species as a dosage form. Nomenclature of powders and species. Technological scheme of production. Equipment for their production. Quality control.
30. Tablets with prolonged action. Prolonged release of substances. Classification of dosage forms with prolonged release.
31. Eye ointments. Bases for eye ointments, characteristic of them. Requiments for eye ointments and bases. A feature of the technology of antibiotic eye ointments.
32. Tablets as a dosage form. Classification of tablets. General characteristic of tablets as a dosage form (appearance, dimensions, etc.).
33. Tablets as a dosage form. Excipients used in tablet technology. Classification of excipients, main substances.
34. Coating of tablets with shells. Purpose of coatings. Classification of coatings. Excipients for coatings.
35. Theoretical foundations of dissolution process. Solvents in factory production of drugs. Classification of solvents. Requirements for solvents. Characteristics of individual representatives
36. Coating of tablets. Classification of coatings. Dragee-coated tablets. Excipients for dragee-like coatings. Equipment. Method of obtaining tablets with dragee coating.
37. Coating of tablets. Classification of coatings. Pressed tablet coatings. Equipment. Multilayer tablets.
38. Granules as a dosage form. Nomenclature. Quality control. Features of pellet technology for children. Equipment used for granules preparation. Excipients in granules technology. General technological scheme of granules manufacturing process.
2.Level 2 skill assessment - solving situational cases (Each case is estimated at 10 points).
1.Recipe: Solutionis Natrii bromidi 1%-50,0
Da. Signa. By 1 teaspoon 2 times a day orally for newborn baby 20 days old
2.Recipe: Analgini 0,25
Coffeini natrii benzoatis 0,1
Misce fiat pulvis
Da tales doses N 20
Signa. By 1 powder 3 times a day orally
3.Recipe: Papaverini hydrochloridi 0,05
Sacchari 0,2
Misce fiat pulvis
Da tales doses N 15
Signa. By 1 powder 2 times a day orally
4.Recipe: Solutionis Natrii chloridi 10 % - 30,0
Sterilizetur!
Da. Signa. For intraveneous injections
5.Recipe: Acidi ascorbinici 0,1
Sacchari 0,2
Misce fiat pulvis
Da tales doses N 30
Signa. By 1 powder 3 times a day orally
6.Recipe: Solutionis Dimedroli 0,5%-10,0
Da. Signa. By 2 drops 3 times a day in both eyes
7.Recipe: Solutionis Glucosi 5 % - 100,0
Da. Signa. By 1 teaspoon 2 times a day for newborn baby 20 days old
8.Recipe: Dimedroli 0,05
Calcii gluconatis 0,2
Misce fiat pulvis
Da tales doses N 15
Signa. By 1 powder 3 times a day orally
9.Recipe: Infus irhizomatis cum radicibus Valerianae ex 5,0 – 100,0
Natrii bromidi 1,0
Coffeini- natrii bensoatis 0,5
Misce. Da. Signa. By 1 tablespoon 3 times a day orally
10.Recipe: Solutionis Acidi nicotinici 0,05%-100,0
Da. Signa. By 1 teaspoon 2 times a day orally for newborn baby 10 days old
11.. Recipe: Solutionis Euphyllini 1% - 100,0
Da. Signa. By 1 tablespoon 3 times a day orally
12.Recipe: Solutionis Acidi glutaminici 1%-100,0
Da. Signa. By 1 teaspoon 2 times a day orally for newborn baby 10 days old
13.Recipe: Solutionis Natrii bromidi 1%-50,0
Signa. By 1 teaspoon 2 times a day orally for newborn baby 20 days old
14.Recipe: Solutionis Acidi glutaminici 2%-200,0
Da. Signa. By 1 tablespoon 3 times a day orally
15.Recipe: Solutionis Novocaini 1%-10,0
Da. Signa. By 2 drops 3 times a day in both eyes
16.Recipe: Infusi rhizomatis cum radicibusValerianae ex 10,0 – 100,0
Natrii bromidi 0,5
Coffeini- natrii bensoatis 0,4
Misce. Da. Signa. By 1 tablespoon 3 times a day orally
17.Recipe: Infusi herbae Leonuri ex 5,0 - 180,0
Analgini 3,0
Misce. Da. Signa. By 1 tablespoon 3 times a day
18.Recipe: Infusi herbae Leonuri ex 5,0 - 180,0
Analgini 1,0
Misce. Da. Signa. By 1 tablespoon 3 times a day
19.Recipe: Solutionis Novocaini 0,5% - 20,0
Sterilizetur!
Da. Signa. For injections. By 2 ml to dissolve benzylpenicillinum, injections every 4 hours.
20.Recipe: Solutionis Natrii bromidi 1%-50,0
Da. Signa. By 1 teaspoon 2 times a day orally for newborn baby 20 days old
21.Recipe: Solutionis Glucosi 5%-50,0
Acidi ascorbinici 0,5
Da. Signa. By 1 teaspoon 2 times a day orally for newborn baby 10 days old
22.Recipe: Solutionis Natrii bromidi 0,5% - 200,0
Coffeini – natrii bensoatis 0,5
Misce. Da. Signa. By 1 tablespoon 3 times a day orally
23.Recipe: Solutionis Natriibromidi 1% - 200,0
Coffeini – natrii bensoatis 0,2
Misce. Da. Signa. By 1 tablespoon 3 times a day orally
24.Recipe: Acidi ascorbinici 0,2
Sacchari 0,3
Misce fiat pulvis
Da tales doses N 15
Signa. By 1 powder 3 times a day orally
25.Recipe: Solutionis Novocaini 0,25% - 20,0
Da tales doses N 5
Sterilizetur!
Da. Signa. For injections. By 5 ml to dissolve benzylpenicillinum injections every 4 hours.
26.Recipe: Solutionis Novocaini 1%-10,0
Da. Signa. By 2 drops 3 times a day in both eyes
27.Recipe: Coffeini natrii bensoatis 0,65
Natrii salicylatis 1,2
Aquae purificatae 85,0
Misce. Da. Signa. By 1 tablespoon 3 times a day
28.Recipe: Solutionis Euphyllini 0,5% - 100,0
Da. Signa. By 1 teaspoon 2 times a day orally for newborn baby 20 days old orally
29.Recipe: Solutionis Natrii bromidi 3%-150,0
Da. Signa. By 1 tablespoon 3 times a day orally
30.Recipe: Solutionis Natriibromidi 0,5% - 200,0
Coffeini – natriibensoatis 0,5
Misce. Da. Signa. By 1 tablespoon 3 times a day orally
31.Recipe: Solutionis Natrii hydrocarbonatis 7 % - 100,0
Sterilizetur!
Da. Signa. For intraveneous injections
32.Recipe: Unguent iStreptocidi 3%-10,0
Da. Signa. To spread on the injured skin
33.Recipe: Unguenti Streptocidi 1%-10,0
Da. Signa. To spread on the injured skin
34.Calculate on equivalents of sodium chloride:
Recipe: SolutionisChininihydrochloridi 1% -20.0
Sodium chloride as required to get isotonic solution
Da. Signa. Eye drops. By 2 drops 2 times a day in the left eye
35.Calculate on equivalents of sodium chloride:
Recipe: SolutionisDicaini 0,5%-20.0
Sodium chloride as required to get
isotonic solution
Da. Signa. By 2 drops 3 times a day in both eyes
36.Calculate on equivalents of sodium chloride:
Recipe: Sol. Papaverini hydrochloridi 2% -50,0
Sodium chloride as required to get isotonic solution
Sterilizetur!
Da. Signa. By 2 ml 2 times a day intramuscular
37.Calculate on equivalents of sodium chloride:
Recipe: Solutionis Magnesii sulfatis 1%-100.0
Sodium chloride as required to get
isotonic solution
Da. Signa. For intraveneous injection
38.Calculate on equivalents of sodium chloride:
Recipe: SolutionisNovocaini 0,5% - 10.0
Sodium chloride as required to get isotonic solution
Da. Signa. By 2 drops 3 times a day in both eyes
39. Calculate on equivalents of sodium chloride:
Recipe: SolutionisDimedroli 0,2% - 10.0
Novocaini 0,05
Sodium chloride as required to get isotonic solution
Da. Signa. By 2 drops 3 times a day in both eyes
40. Calculate on equivalents of sodium chloride:
Recipe: Solutionis Dimedroli1% -10.0
Sodium chloride as required to get
isotonic solution
Sterilize!
Da. Signa. By 2 drops 2 times a day in the left eye
41.Calculate on equivalents of sodium chloride:
Recipe: Solutionis Glucosi 1%-10.0
Sodium chloride as required to get isotonic solution
Da. Signa. By 2 drops 3 times a day in both eyes
42.Calculate on equivalents of sodium chloride:
Recipe: Solutionis Riboflavini 0.02% - 10.0
Acidi ascorbinici 0,02
Kalii iodidi 0,1
Sodium chloride as required to get isotonic solution
Da. Signa. By 2 drops 3 times a day in both eyes
43. Calculate on equivalents of sodium chloride:
Recipe: SolutioAcidiascorbinici 0,5% -20.0
Sodium chloride as required to get
isotonic solution
Sterilize!
Da. Signa. By 2 drops 2 times a day in the left eye
44.Calculate on equivalents of sodium chloride:
Recipe: Solutionis Riboflavini 0.02% - 10.0
Acidi ascorbinici 0,03
Acidi nicotinici 0,02
Sodium chloride as required to get isotonic solution
45.Calculate on equivalents of sodium chloride:
Recipe: Solutionis Acidi scorbinici 0.5% - 10.0
Glucosi 0,1
Sodium chloride as required to get isotonic solution
Da. Signa. By 2 drops 3 times a day in both eyes
46.Calculate on equivalents of sodium chloride:
Recipe: Solutionis Riboflavini 0.02% - 10.0
Acidi ascorbinici 0,03
Acidi nicotinici 0,02
Sodium chloride as required to get isotonic solution
Da. Signa. By 2 drops 3 times a day in both eyes
47. Calculate on equivalents of sodium chloride:
Recipe: SolutioAcidi borici 1% -10.0
Sodium chloride as required to get
isotonic solution
Da. Signa. Eye drops. By 2 drops 2 times a day in the left eye
48.Calculate on equivalents of sodium chloride:
Recipe: Solutionis Pilocarpini hydrochloridi 1% - 10.0
Sodium chloride as required to get isotonic solution
Da. Signa. By 2 drops 3 times a day in both eyes
49.Calculate on equivalents of sodium chloride:
Recipe: Solutionis Novocaini 0.5% - 10.0
Dimedroli 0,03
Sodium chloride as required to get isotonic solution
Da. Signa. By 2 drops 3 times a day in both eyes
50. Calculate on equivalents of sodium chloride:
Recipe: Solutionis Pilocarpini hydrochloridi 1%-10.0
Sodium chloride as required to get
isotonic solution
Da. Signa. Eye drops. By 2 drops 2 times a day in the left eye
51. Calculate on equivalents of sodium chloride:
Recipe: Solutionis Atropini sulfatis 1%-10.0
Sodium chloride as required to get
isotonic solution
Da. Signa. Eye drops. By 2 drops 2 times a day in the left eye
52.Calculate on equivalents of sodium chloride:
Recipe: Solutionis Ephedrini hydrochloridi 1% -20.0
Sodium chloride as required to get isotonic solution
Da. Signa. Eye drops. By 2 drops 2 times a day in the left eye
53. Calculate on equivalents of sodium chloride:
Recipe: Solutionis Acidi ascorbinici 1%-10.0
Sodium chloride as required to get
isotonic solution
Da. Signa. Eye drops. By 2 drops 2 times a day in the left eye
54. Calculate on equivalents of sodium chloride:
Recipe: Solutio Ephedrini hydrochloride 1% -20.0
Sodium chloride as required to get
isotonic solution
Da. Signa. Eye drops. By 2 drops 2 times a day in the left eye
55. Calculate on equivalents of sodium chloride:
Recipe: Solutionis Acidi ascorbinici 0,3% -10.0
Sodium chloride as required to get
isotonic solution
Sterilize!
Da. Signa. Eye drops. By 2 drops 2 times a day in the left eye
56.Calculate on equivalents of sodium chloride:
Recipe: Solutionis Ephedrini hydrochloridi 2% -30.0
Sodium chloride as required to get
isotonic solution
Da. Signa. Eye drops. By 2 drops 2 times a day in the left eye
57.Calculate on equivalents of sodium chloride
Recipe: Sol. Dimedroli 1% -20,0
Sodium chloride as required to get isotonic solution
Sterilizetur!
Da. Signa. Eye drops. By 2 drops 3 times a day in both eyes
58. Calculate on equivalents of sodium chloride:
Recipe: SolutioNovocaini 1%-10.0
Sodium chloride as required to get
isotonic solution
Sterilize!
Da. Signa. Eye drops. By 2 drops 2 times a day in the left eye
59. Calculate on equivalents of sodium chloride:
Recipe: SolutionisAcidinicotinici 0,5% -20.0
Sodium chloride as required to get
isotonic solution
Sterilize!
Da. Signa. By 2 drops 2 times a day in the left eye
60.Calculate on equivalents of sodium chloride:
Recipe: Solutionis Riboflavini 0.02% - 10.0
Acidi borici 0,03
Glucosi 0,1
Sodium chloride as required to get isotonic solution
Da. Signa. By 2 drops 3 times a day in both eyes
61.Calculate on equivalents of sodium chloride:
Recipe: Solutionis Dicaini 0.2% - 10.0
Dimedroli 0,03
Sodium chloride as required to get isotonic solution
Da. Signa. By 2 drops 3 times a day in both eyes
62. Calculate on equivalents of sodium chloride:
Recipe: SolutionisDicaini 1% -10.0
Sodium chloride as required to get
isotonic solution
Sterilize!
Da. Signa. Eye drops. By 2 drops 2 times a day in the left eye
63. Calculate on equivalents of sodium chloride:
Recipe: Solutionis Resorcini 1% -10.0
Sodium chloride as required to get
isotonic solution
Sterilize!
Da. Signa. Eye drops. By 2 drops 2 times a day in the left eye
64.Calculate on equivalents of sodium chloride:
Recipe: Solutionis Kalii iodidi 0.5% - 10.0
Sodium chloride as required to get isotonic solution
Da. Signa. By 2 drops 3 times a day in both eyes
65. Calculate on equivalents of sodium chloride:
Recipe: Solutionis Natrii hydrocarbonatis 1% -150,0
Sodium chloride as required to get isotonic solution
Sterilizetur!
Da. Signa. Lotion for eyes
66. Calculate on equivalents of sodium chloride:
Recipe: Sol. Glucosi 2% -200,0
Sodium chloride as required to get isotonic solution
Sterilizetur!
Da. Signa. For injections
67.Calculate on equivalents of sodium chloride:
Recipe: Solutionis Glucosi 0.2% - 10.0
Acidi ascorbinici 0,05
Sodium chloride as required to get isotonic solution
Da. Signa. By 2 drops 3 times a day in both eyes
68.Calculate on equivalents of sodium chloride:
Recipe: Solutionis Atropini sulfatis 1%-20.0
Sodium chloride as required to get isotonic solution
Da. Signa. Eye drops. By 2 drops 2 times a day in the left eye
69. Calculate on equivalents of sodium chloride:
Recipe: Solutionis Pilocarpini hydrochloridi 1% -10.0
Sodium chloride as required to get
isotonic solution
Sterilize!
Da. Signa. Eye drops. By 2 drops 2 times a day in the left eye
70.Calculate on equivalents of sodium chloride:
Recipe: Solutionis Acidi ascorbinici 0,5% - 10.0
Acidi nicotinici 0,03
Sodium chloride as required to get isotonic solution
Da. Signa. By 2 drops 3 times a day in both eyes
71.Calculate on equivalents of sodium chloride:
Recipe: Solutionis Acidi ascorbinici 0.5% - 10.0
Glucosi 0,1
Sodium chloride as required to get isotonic solution
Da. Signa. By 2 drops 3 times a day in both eyes
72. Calculate on equivalents of sodium chloride:
Recipe: Solution Zincisulfatis 0,5%-10.0
Acidi borici as required to get isotonic solution
Da. Signa. Eye drops. By 2 drops 2 times a day in the left eye
73.Calculate on equivalents of sodium chloride:
Recipe: Solutionis Glucosi 1% - 10.0
Novocaini 0,05
Sodium chloride as required to get isotonic solution
Da. Signa. By 2 drops 3 times a day in both eyes
CASES for alcohol dilution:
1. Find the density of an alcohol-water solution containing 29.3% (by volume) alcohol and located at a temperature of +22°C.
2.How much 95% alcohol and water will be required to get 375 kg of 40% alcohol? What volume of anhydrous alcohol at 20 ºC is contained in the resulting solution?
3. Find the density of an alcohol-water solution containing 70% alcohol and located at a temperature of +28°C.
4. It is necessary to obtain 15litres of 20% alcohol from of 70% available. Find contraction.
5. Find the density of an alcohol-water solution containing 84.3% alcohol and located at a temperature of +16°C.
6. How many kg of 95% alcohol do you need to take to get 120 Kg of 50% alcohol?
7. It is necessary to obtain 1.5litres of 40% alcohol from 70% alcohol. Find contraction.
8. How many kg of 90% alcohol do you need to take to get 10 kg of 55% alcohol?
9. It is necessary to obtain 10litres of 90% alcohol from 95.12% alcohol and water? What is the contraction?
10. How many kg of 80% alcohol do you need to take to get 38 kg of 45% alcohol?
11. It is necessary to obtain20litres95% alcohol from 96.45% alcohol and water? What is the contraction?
12. How many kg of 96% alcohol do you need to take to get 183 kg of 50% alcohol?
13.It is necessary to obtain10 litres of 40% alcohol from 94.55% alcohol and water? What is the contraction?
14. How many kg of 90% alcohol do you need to take to get 386 kg of 30% alcohol?
15. It is necessary to obtain20 litres of 70% alcohol from 93.52% alcohol and water? What is the contraction?
16. How many kg of 90% alcohol do you need to take to get 18 kg of 30% alcohol?
17. It is necessary to obtain2 litres of 70% alcohol from 93.85% alcohol and water? What is the contraction?
18.How much 96% alcohol and water would be required to get 285 kg of 40% alcohol? What volume of anhydrous alcohol at 20 ºC is contained in the resulting solution?
19. It is necessary to obtain8 litres of 90% alcohol from 94.55% alcohol and water? Find the quantity of anhydrous ethanol in this solution.
20. How much of 96%alcohol will be necessary to get 4 kg of 60% alcohol. Find contraction.
21.How much will it take 90% alcohol and water to get 25 Kg of 60% alcohol? What volume of anhydrous alcohol at 20 ºC is contained in the resulting solution?
22. Prepare 840 liters of 20% alcohol from 95% alcohol and water? What is the contraction?
23. How many kg of 70% alcohol you need to take to get 18 Kg of 40% alcohol?
24. Obtain 100 litres of 80% alcohol from the available 95% alcohol. Find contraction.
25. How many kg of 90% alcohol you need to take to get 15 Kg of 70% alcohol?
26. How many litres of 96% alcohol do you need to take to get 115 liters of 50% alcohol? Find contraction.
27. How many kg of 40% alcohol you need to take to get 12 Kg20% alcohol? Register alcohol.
28.Get 15 l20% alcohol out of 70% available. Find contraction.
29. How many kg of 95% alcohol you need to take to get 20 Kg of 40% alcohol?
30.It is necessary to obtain 8 litres of 90% alcohol from 96.5% alcohol and water? What is the contraction?
31. Find the density of an alcohol-water solution containing 57.3% (by volume) alcohol at a temperature of +36°C.
32. Get 5.5 kg of 35% alcohol from the available 96%. Find contraction.
33. Find the density of an alcohol-water solution containing 12.6% (by volume) alcohol and located at a temperature of +26°C.
34. Get 1 kg38% alcohol out of 95% available. Register alcohol.
35. A glass alcohol meter immersed in a water-alcohol solution at 36°C dropped to a scale mark of 97.0. Determine the alcohol concentration.
36.It is necessary to obtain 2.5 litres of 70% alcohol from 90% available. Find contraction.
37. The density of the aqueous-alcohol solution is 0.85000 at a temperature of +24°C. Determine the alcohol concentration in percent by volume in the alcohol-water mixture.
38.How to prepare 186 liters of 80% alcohol from 96.5% alcohol and water? What is the contraction? Make a record of the alcohol received.
39. Find the density of an alcohol-water solution containing 84.2% (by volume) alcohol at a temperature of + 16°C.
40.How to prepare 2 liters of 40% alcohol from 93.85% alcohol and water? What is the contraction? Make a record of the alcohol received.
41.Find the density of an alcohol-water solution containing 62.3% (by mass) alcohol at a temperature of -8°C.
42.How many liters of water and 96% alcohol are needed to make 320 liters of 70% alcohol? Find contraction. Record alcohol.
43. What is the alcohol concentration in % by weight if the alcohol concentration by volume is 61.3%
44. Get 15.5 liters of 45% alcohol from the available 98%. Find contraction.
45. Find the density of an alcohol-water solution containing 92.6% (by volume) alcohol at a temperature of +4°C.
46. How many kg of 90% alcohol do you need to take to get 36 kg of 70% alcohol?
47. Find the density of an alcohol-water solution containing 95% (by weight) alcohol and located at a temperature of 0°C.
48. Get 15 liters of 50% alcohol from the available 95%. Find contraction.
49. Find the density of an alcohol-water solution containing 96.3% (by weight) alcohol and located at a temperature of +23°C.
50. Get 5.5 kg of 35% alcohol from the available 96%. Find contraction.
51. A metal alcohol meter with a 50 weight, immersed in a water-alcohol solution, dropped to a scale division of 6.6 at a temperature of -6.5°C. Determine the alcohol concentration.
52. How many kg of 96% alcohol you need to take to get 20 Kg 70% alcohol?
53. What is the alcohol concentration in % by weight if the alcohol concentration by volume is 90.25%
54.How to prepare 186 L of 80% alcohol from 96.5% alcohol and water? What is the contraction? Make a record of the alcohol received.
55. Find the density of an alcohol-water solution containing 72.8% (by mass) alcohol and located at a temperature of +24°C.
56.How to prepare 372 liters of 20% alcohol from 96.5% alcohol and water? What is the contraction? Make a record of the alcohol received.
57. Find the density of an alcohol-water solution containing 84.6% (by mass) alcohol and located at a temperature of +14°C.
58.How to make 100 liters of 70% alcohol from 93.5% alcohol and water? What is the contraction? Make a account of the alcohol.
59. Find the density of an alcohol-water solution containing 94.2% (by mass) alcohol and located at a temperature of +24°C.
60.How to make 200 liters of 50% alcohol from 98.5% alcohol and water? What is the contraction? Make a account of the alcohol.
61. Find the density of an alcohol-water solution containing 78.5% (by mass) alcohol and located at a temperature of - 10°C.
62.How to make 350 liters of 40% alcohol from 96.5% alcohol and water? What is the contraction? Make an account of the alcohol.
63. Find the density of an alcohol-water solution containing 70.2% (by mass) alcohol and located at a temperature of +18°C.
64.How to make 120 liters of 90% alcohol from 97.3% alcohol and water? What is the contraction? Make an account of the alcohol.
65. A metal alcohol meter with a 60 weight, immersed in a water-alcohol solution, dropped to a scale division of 8.2 at a temperature of -10.5°C. Determine the alcohol concentration.
66. It is necessary to obtain 1 liter of 33% alcohol from 90% alcohol. Find contraction.
67. The density of the aqueous-alcohol solution is 0.81144 at a temperature of +20°C. Determine the alcohol concentration in percent by volume and % by mass in the alcohol-water mixture.
68.How much 98% alcohol and water will be required to get 75 kg of 50% alcohol? What volume of anhydrous alcohol at 20 ºC is contained in the resulting solution?
69. Find the density of an alcohol-water solution containing 50.4% (by mass) alcohol and located at a temperature of -2°C.
70. How many kg of 80% alcohol do you need to get 48 kg of 30% alcohol? Make an account of the alcohol.
71.How to prepare 175 liters of 50% alcohol from 95.5% alcohol and water? What is the contraction? Make an account of the alcohol.
72. Based on the reading of a glass alcohol meter of 63.2 at a temperature of +31 °C, determine the concentration of alcohol in the alcohol-water mixture as a percentage by weight and as a percentage by volume.
73. Based on the reading of a glass alcohol meter of 78.4 at a temperature of +23 °C, determine the concentration of alcohol in the alcohol-water mixture as a percentage by weight and as a percentage by volume.
74.Get 2.5 liters of 70% alcohol from 90% available. Find contraction.
75. Based on the reading of a glass alcohol meter of 86.4 at a temperature of +18,4 °C, determine the concentration of alcohol in the alcohol-water mixture as a percentage by weight and as a percentage by volume.
76. How many kg of 96% alcohol you need to take to get 18 Kg50% alcohol? Account of alcohol.
77. Reading of a glass alcohol meter is 96.2 at a temperature of +28,4 °C, determine the concentration of alcohol in the alcohol-water mixture as a percentage by weight and as a percentage by volume.
78. How many kg of 96% alcohol you need to take to get 20 Kg 70% alcohol?
EXAMPLE OF TICKET
Kazan State Medical University
of the Ministry of Health of the Russian Federation
Institute of Pharmacy
Pharmaceutical Technology
Ticket number 50
Level 1 - knowledge assessment
1. Give an answer to the theoretical question:
1. Powders and Species as a dosage form. Nomenclature of powders and species. Technological scheme of production. Equipment for their production. Quality control.
2.Level 2 skill assessment - solving situational cases (Each case is estimated at 10 points).
The situational case is described according to the following algorithm:
· write the prescription in Latin;
· determine the type of dosage form;
· make a pharmaceutical analysis (control doses if necessary etc.);
· make the necessary calculations;
· describe the theoretical points of technology of the drug;
· describe the type of packaging of the medicinal product and design of the label for dispensing;
· describe the technology of the medicinal product according to the individual prescription;
· set the quality criteria for the manufactured product;
· write the passport of written control;
· set the expiration date of the manufactured product.
Recipe: Solutionis Dimedroli 0,5%-10,0
Da. Signa. By 2 drops 3 times a day in both eyes
3.Calculate on equivalents of sodium chloride:
Recipe: Solutionis Riboflavini 0.02% - 10.0
Acidi borici 0,03
Glucosi 0,1
Sodium chloride as required to get isotonic solution
Da. Signa. By 2 drops 3 times a day in both eyes
4. Find the density of an alcohol-water solution containing 94.2% (by mass) alcohol and located at a temperature of +24°C.
5.How to make200 liters of 50% alcohol from 98.5% alcohol and water? What is the contraction? Make account of the alcohol.
Note: The maximum number of points for answering on a ticket is 50 points (5 questions x 10 points = 50)
level 3 - assessment of proficiency - certification of practical skills - maximum 50 points (was made previously)
The final mark for the exam is 100 points.
